Marcelo Farina Selected Research

Capsaicin (Zostrix)

4/2009	Antinociceptive properties of the hydroalcoholic extract and the flavonoid rutin obtained from Polygala paniculata L. in mice.
7/2008	Antinociceptive effect of the Polygala sabulosa hydroalcoholic extract in mice: evidence for the involvement of glutamatergic receptors and cytokine pathways.

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Marcelo Farina Research Topics

Disease

18	Mitochondrial Diseases (Mitochondrial Disease) 01/2022 - 12/2007
9	Parkinson Disease (Parkinson's Disease) 01/2022 - 01/2011
8	Cognitive Dysfunction 02/2024 - 01/2012
8	Body Weight (Weight, Body) 01/2021 - 11/2004
8	Poisoning 10/2020 - 12/2007
7	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 02/2013
7	Neuroblastoma 08/2020 - 08/2009
5	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 04/2013
5	Huntington Disease (Huntington's Disease) 09/2018 - 03/2012
5	Hypercholesterolemia 04/2014 - 01/2012
4	Neuroinflammatory Diseases 02/2023 - 01/2014
4	Memory Disorders (Memory Loss) 02/2016 - 02/2007
3	Gliosis 01/2023 - 01/2014
3	Hyperlipoproteinemia Type II (Familial Hypercholesterolemia) 01/2020 - 10/2013
3	Atherosclerosis 02/2017 - 11/2008
3	Glioma (Gliomas) 09/2013 - 09/2010
2	COVID-19 01/2023 - 01/2022
2	Ischemic Stroke 01/2023 - 08/2021
2	Dementia (Dementias) 11/2020 - 04/2014
2	Cardiovascular Diseases (Cardiovascular Disease) 02/2017 - 12/2012
2	Dyskinesias (Dyskinesia) 10/2016 - 01/2011
2	Neoplasms (Cancer) 12/2015 - 11/2004
2	Depressive Disorder (Melancholia) 12/2014 - 02/2013
2	Hypothyroidism 01/2013 - 09/2007
2	Amyloid Plaque 02/2012 - 02/2007
2	Pain (Aches) 12/2011 - 04/2009
2	Necrosis 04/2009 - 07/2008
2	Alcoholic Liver Diseases (Alcoholic Liver Disease) 05/2006 - 02/2006
2	Anemia 05/2005 - 11/2004
1	Antisocial Personality Disorder (Antisocial Personality) 02/2024
1	Iron Overload 11/2023
1	Bipolar Disorder (Manic Depressive Psychosis) 09/2023
1	Hearing Loss (Hearing Impairment) 09/2023
1	Diabetes Complications 09/2023
1	Brain Ischemia (Cerebral Ischemia) 09/2023
1	Mycoses (Diseases, Fungus) 09/2023
1	Virus Diseases (Viral Diseases) 01/2023
1	Stroke (Strokes) 01/2023

Drug/Important Bio-Agent (IBA)

13	AntioxidantsIBA 01/2019 - 02/2007
10	Probucol (Lorelco)FDA Link 01/2023 - 03/2012
7	Glutamic Acid (Glutamate)FDA Link 01/2023 - 04/2004
7	CholesterolIBA 01/2020 - 12/2012
6	AcetylcholinesteraseIBA 02/2024 - 01/2008
6	LDL Receptors (LDL Receptor)IBA 01/2020 - 01/2012
6	MercuryIBA 02/2017 - 01/2005
5	Cholinergic Agents (Cholinergics)IBA 10/2020 - 01/2008
5	EnzymesIBA 08/2020 - 09/2007
5	Sulfhydryl Compounds (Thiols)IBA 08/2017 - 01/2005
5	Peptides (Polypeptides)IBA 07/2015 - 02/2007
5	Amyloid (Amyloid Fibrils)IBA 07/2015 - 02/2012
4	IronIBA 02/2024 - 01/2022
4	PeroxidesIBA 08/2020 - 12/2009
4	Glutathione (Reduced Glutathione)IBA 01/2019 - 02/2007
4	diphenyldiselenideIBA 01/2019 - 04/2009
4	Oxidopamine (6 Hydroxydopamine)IBA 05/2016 - 01/2010
4	Malathion (Karbofos)FDA LinkGeneric 03/2016 - 01/2008
4	LipidsIBA 03/2016 - 12/2012
4	LDL Lipoproteins (beta Lipoproteins)IBA 01/2016 - 11/2008
4	oxidized low density lipoproteinIBA 01/2016 - 11/2008
3	SeleniumIBA 01/2023 - 05/2005
3	Therapeutic UsesIBA 08/2022 - 11/2004
3	MetalsIBA 01/2022 - 11/2020
3	Oxidants (Oxidizing Agents)IBA 01/2019 - 12/2007
3	Proteins (Proteins, Gene)FDA Link 01/2018 - 04/2009
3	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 10/2017 - 01/2011
3	CalciumIBA 01/2017 - 11/2011
3	succinobucol (AGI 1067)IBA 01/2017 - 03/2013
3	Neuroprotective AgentsIBA 01/2015 - 01/2011
3	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 02/2013 - 01/2010
3	OximesIBA 12/2011 - 01/2008
3	Glutathione PeroxidaseIBA 08/2009 - 01/2008
2	Selenoproteins (Selenoprotein)IBA 01/2023 - 11/2011
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022 - 09/2010
2	ManganeseIBA 11/2020 - 09/2015
2	Antidepressive Agents (Antidepressants)IBA 01/2018 - 12/2014
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 10/2016 - 11/2011
2	3-nitropropionic acidIBA 03/2016 - 03/2013
2	Succinate Dehydrogenase (Fumarate Reductase)IBA 03/2016 - 03/2013
2	GuanosineIBA 12/2014 - 04/2004
2	LDL CholesterolIBA 04/2014 - 12/2012
2	Organoselenium CompoundsIBA 08/2013 - 11/2004
2	Propylthiouracil FDA Link 01/2013 - 09/2007
2	Glucose (Dextrose)FDA LinkGeneric 01/2013 - 11/2009
2	pralidoxime (Protopam Chloride)FDA Link 12/2011 - 09/2010
2	Thiobarbituric Acid Reactive SubstancesIBA 04/2009 - 01/2005
2	Capsaicin (Zostrix)FDA Link 04/2009 - 07/2008
2	Interleukin-1beta (Interleukin 1 beta)IBA 04/2009 - 07/2008
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2009 - 07/2008
2	SolutionsIBA 08/2007 - 04/2006
1	Monounsaturated Fatty AcidsIBA 11/2023
1	Oleic Acid (Oleate)IBA 11/2023
1	ebselenIBA 09/2023
1	mancozebIBA 09/2023
1	Endothelin-1 (Endothelin 1)IBA 01/2023
1	Vasoconstrictor AgentsIBA 01/2023
1	Phospholipid Hydroperoxide Glutathione PeroxidaseIBA 01/2022
1	Peptide Hydrolases (Proteases)FDA Link 01/2022
1	Protease Inhibitors (Protease Inhibitor)IBA 01/2022

Therapy/Procedure

3	Therapeutics 01/2022 - 11/2010
2	Injections 01/2023 - 12/2006